O Polypodium leucotomos no melasma: uma revisão
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Abstract
Introduction: Polypodium leucotomos has some properties on the human body and mainly on the skin. Being used as an adjuvant in the treatment and prevention of various pathologies such as melasma. Objective: This study reviews the literature to identify the impact of Polypodium leucotomos in the treatment of melasma. Material and Method: Analysis of data in the bases of academic articles in health: Scielo, Medline, Lilacs with the descriptors in Health Sciences (DeCS): Phytotherapy; Melasma and dietary supplements, with no year restrictions, in Portuguese and English. Where the eligibility criteria were considered for inclusion, the original articles clinical trials, case control, systematic review and meta-analysis, animal studies, in vitro and adult patients, Result: 31 studies were found, 13 were included and 18 excluded by do not meet the eligibility criteria. Conclusion: The literature survey allowed us to conclude that among the various properties of Polypodium leucotomos, the antioxidant, anti-inflammatory, photoprotective and immunomodulatory properties stand out, having a considerable impact on improving the quality of life of melasma patients, being a whitening factor and protective in the disease. However, more randomized clinical studies should be carried out to confirm its effects and establish the appropriate dose as an adjunct to the treatment of melasma.
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